Advanced Microneedling at The MSK Clinic Physio

Advanced Skin Rejuvenation & Recovery Support

Exosomes are tiny extracellular vesicles involved in cell-to-cell communication. They have attracted growing interest in regenerative aesthetics because of their potential role in skin repair and cellular signalling.

Exosome-based skincare formulations are being investigated for their potential to support skin hydration, recovery and rejuvenation.
When used alongside microneedling, the intention is to complement the skin’s natural renewal process.

• Potential Benefits Being Investigated
• Improved skin hydration
• Support for skin recovery
• Improved appearance of fine lines
• Smoother-looking skin
• Improved overall skin quality

Who may consider it?

Patients interested in advanced skin rejuvenation who wish to explore newer regenerative skincare technologies.
Important: Exosome-assisted microneedling is an emerging treatment. Clinical evidence is still developing, and additional benefits beyond microneedling alone have not been conclusively established.

The suitability of any exosome formulation depends on its ingredients, intended use, regulatory status and compatibility with microneedling.

Skin Quality, Hydration & Regenerative Aesthetics

Polynucleotides are purified DNA-derived compounds used in some injectable skin-rejuvenation treatments.
They are increasingly used in aesthetic medicine for their potential to support skin quality, hydration and tissue repair.

At The MSK Clinic Physio, polynucleotide treatments can be considered as part of a personalised skin-rejuvenation programme alongside microneedling.

Depending on the formulation and its approved intended use, polynucleotides may be administered as a separate treatment rather than applied directly into microneedled skin.

• Potential Benefits
• Improved skin hydration
• Improved appearance of fine lines
• Support for skin quality and elasticity
• Smoother-looking skin
• Gradual improvement in overall skin appearance

Polynucleotide treatments are particularly popular among patients seeking subtle, natural-looking improvements rather than changes to facial volume.

Recommended treatment plan: Determined during consultation, according to the product, treatment method and skin concerns.
Evidence for combined treatment protocols remains limited, and outcomes cannot be guaranteed.

Improve the appearance of fine lines, wrinkles, acne scars, enlarged pores and uneven skin texture. Facial microneedling stimulates collagen production to support smoother, firmer and healthier-looking skin.

Target fine lines, crepey skin and uneven texture around the neck. Microneedling can help improve skin quality and firmness in this delicate area.

Address fine lines, sun-related skin changes and uneven texture across the upper chest and décolletage, helping the skin appear smoother and more refreshed.

Scalp microneedling may be considered as part of a personalised hair-loss treatment programme. Emerging evidence suggests it may help support hair growth in certain types of hair loss, particularly when combined with established treatments.

A consultation is required to assess the cause of hair loss and determine whether microneedling is appropriate.

Microneedling can help improve the appearance of selected surgical scars, including Caesarean section (C-section) scars, by encouraging collagen remodelling and improving skin texture.

Treatment may help with:

• Uneven or irregular scar texture
• Mildly raised or depressed scars
• Scar appearance and skin quality
• Selected mature surgical scars

Treatment is only performed once the scar has fully healed and following an assessment of scar maturity, skin condition and suitability.

Microneedling may help reduce the appearance of stretch marks by stimulating collagen remodelling within the skin.

Common treatment areas include:

• Abdomen and tummy
• Hips and thighs
• Buttocks
• Upper arms

Areas affected by pregnancy or weight changes

We can also assess selected scars resulting from previous injuries, surgery or acne. Treatment aims to improve the scar’s appearance and texture rather than remove it completely.

Not all scars are suitable for microneedling, particularly those prone to keloid formation.

Yes! Even scars that are several years old may respond to microneedling.

Although scars continue to mature naturally over approximately 12–18 months or longer, collagen remodelling can still be stimulated in established scars.

A course of approximately 3–6 treatments, commonly spaced a few weeks apart, may be recommended depending on the scar’s age, depth, texture and response to treatment.

C-section scars can be assessed for microneedling once fully healed. Treatment may help improve uneven texture, mild depression and the overall appearance of the scar.

However, microneedling does not correct deeper scar adhesions or restrictions in the underlying tissues.
At The MSK Clinic Physio, we consider both your scar’s appearance and any associated tissue restrictions, which helps us recommend the most appropriate treatment approach.

Traditional microneedling works by creating controlled micro-injuries that stimulate the skin’s natural repair response. Exosome-based products are being investigated as complementary treatments, but there is currently insufficient high-quality evidence to establish that they consistently improve outcomes beyond microneedling alone.

They are different technologies with different formulations and methods of use. There is currently insufficient comparative clinical evidence to say that one is universally better. Your clinician can discuss the evidence, potential benefits and limitations.

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Yes. Microneedling can improve the appearance of certain types of atrophic acne scars by stimulating collagen remodelling. Results depend on the type and severity of scarring.

Microneedling is generally avoided over active inflammatory acne lesions because of the risk of irritation and spreading infection. We will assess your skin and advise on suitable treatment options.

No. Treatment may be unsuitable for patients with certain skin infections, impaired wound healing, a history of problematic scarring or other contraindications. A consultation is essential.

Selected areas around the eyes may be treated using carefully adjusted protocols. The suitability of treatment depends on your anatomy, skin condition and the device’s intended use.

Results vary depending on your skin, age, lifestyle and treatment course. Maintenance treatments and appropriate skincare may help preserve improvements.